Five gene signatures were identified in the prediction of overall survival in resectable pancreatic cancer
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چکیده
منابع مشابه
the study of aaag repeat polymorphism in promoter of errg gene and its association with the risk of breast cancer in isfahan region
چکیده: سرطان پستان دومین عامل مرگ مرتبط با سرطان در خانم ها است. از آنجا که سرطان پستان یک تومور وابسته به هورمون است، می تواند توسط وضعیت هورمون های استروئیدی شامل استروژن و پروژسترون تنظیم شود. استروژن نقش مهمی در توسعه و پیشرفت سرطان پستان ایفا می کند و تاثیر خود را روی بیان ژن های هدف از طریق گیرنده های استروژن اعمال می کند. اما گروه دیگری از گیرنده های هسته ای به نام گیرنده های مرتبط به ا...
15 صفحه اولA 25-gene classifier predicts overall survival in resectable pancreatic cancer
BACKGROUND Pancreatic carcinoma is one of the most lethal human cancers. In patients with resectable tumors, surgery followed by adjuvant chemotherapy is the only curative treatment. However, the 5-year survival is 20%. Because of a strong metastatic propensity, neoadjuvant chemotherapy is being tested in randomized clinical trials. In this context, improving the selection of patients for immed...
متن کاملAuthor’s response to reviews Title: A 25-gene classifier predicts overall survival in resectable pancreatic cancer Authors:
Title: A 25-gene classifier predicts overall survival in resectable pancreatic cancer Authors: David Birnbaum ([email protected]) Pascal Finetti ([email protected]) Alexia Lopresti ([email protected]) Marine Gilabert ([email protected]) Flora Poizat ([email protected]) Jean-Luc Raoul ([email protected]) Jean-Robert Delpero ([email protected]...
متن کاملThe concentration of D-dimers in portal blood positively correlates with overall survival in patients with non-resectable pancreatic cancer
BACKGROUND Several recent studies provide evidence that D-dimer (DD) concentration in peripheral blood correlates negatively with overall survival (OS) in patients with pancreatic ductal adenocarcinoma (PDAC). Contrarily, there are recent evidence indicating that preoperative plasma fibrinogen, but not D-dimer might represent a prognostic factor in non-metastatic gastrointestinal cancers. MET...
متن کاملCombining Gene Signatures Improves Prediction of Breast Cancer Survival
BACKGROUND Several gene sets for prediction of breast cancer survival have been derived from whole-genome mRNA expression profiles. Here, we develop a statistical framework to explore whether combination of the information from such sets may improve prediction of recurrence and breast cancer specific death in early-stage breast cancers. Microarray data from two clinically similar cohorts of bre...
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ژورنال
عنوان ژورنال: BMC Surgery
سال: 2020
ISSN: 1471-2482
DOI: 10.1186/s12893-020-00856-y